As far as the actual feel and performance of the shoe, it is said to be somewhat like "wearing a sock," clearly an indication of the single fabric construction and connection to barefoot running. At $160 a pair, this is not a shoe for the casual runner, and it may not be for everyone. Certainly, there is no reason to believe this shoe is a necessary purchase for someone who wants to revert to less structure and more natural and barefoot-style running. In fact, it's not a stretch to say that anyone in nearly any shoe can "run barefoot while wearing shoes." In reality, barefoot running is all about the gait and not really at all about the shoes. The key is to run, as if sprinting - or as McDougal says, "like you would if you had to chase a toddler into the street while in bare feet." Basically, natural runners land on the balls of their feet, not the heels. The heel strike - and the potential damage and wear/tear - results from the more padded shoes of the past thirty years that allowed runners to land on their heels. That's not what a runner should do.
And, if a runner wants a bit of protection - especially for street or trail running - the thin barefoot-like shoe doesn't have to be Nike. For as Vanhemert implies, Nike is sort of late to this game. Companies like Merrel have provided barefoot shoes for years. Newton is another great low-structure shoe company and Adidas has some great styles as well.